In my opinion, put everything that isnt the CPU in one loop (gpu, mosfet, nb and sb etc) in one loop, and have the other loop dedicated to the CPU only, especially since you basically have the most restrictive CPU block ever concieved, it'll work best in its own loop with nothing else to stand in its way, I have a similar setup so i've messed aroudn with this, otherwise congrtualations on a brilliant looking build so far, good luck and enjoy!