There should have to be no changes using two sticks of RAM just to boot. You may have to manually set timings to get them at SPD, but it should still boot. Marking the MB with UV is a good idea, as some companies are quick to send the same part right back. I just can't see how its not a MB issue if the RAM is good. The exception to this is the well known problem of trying to load Vista pre-SP1 with 4gigs of RAM installed.
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