at first EasyTune 6 wasn't working for me either. I had been using a hard drive off my X38 board and plugged it into this board and it took. I had SP2 installed on my Vista Ult. x64 and EasyTune 6 would give an AppCrash error and then when I clicked continue it would give me a windows sockets initialization error. Not sure if you all got that same error or not.

I thought maybe it was SP2, so I reinstalled Vista Ult x64 and loaded EasyTune 6 just after my lan drivers and it worked fine. I then installed SP2 then my drivers and it still worked.

Hope this helps someone.
-=Mark=-