Those are nice 24/7 settings, if nothing better is gained.
You can try 100x48 with same or slightly higher voltage to see if there is effect from higher/lower multi.
Also try playing with CPU PLL (1.25V- 2.00V), and BCLK Skew/PCIE CLK Skew -1/-10, -2/-20, +1/+5, +1/+10, +2/+10.
Could be that CPU is not such a great one.
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