What speed is your PCIE bus running at? I have noticed the USB ports do funky things when PCIE is over 100MHz. Eg. My Logitech G5 mouse starts intermittently failing at about 105MHz, and my usb3 ports only work as usb2 when over 100MHz. I just leave it on auto these days. I used to have to change it to get high bclocks but it doesn't seem necessary with newer bioses.

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