P8P67 NON-pro only supports CF, and has one x16 slot that runs full-speed. When the second slot is populated for crossfire it goes down to x4 or x1 mode (x4 if no other devices are in use except the two video cards, x1 otherwise) while the main slot goes to x8.
The P8P67 PRO has SLI and CF support with x8/x8 in the two slots for those setups (i.e. the crippled performance of the NON-pro model in CF/dual card config isn't the case on the PRO). Additionally it features an Intel NIC vs. the Realtek one of the NON-pro, and better phase regulation as well as a bunch of other more minor features/niceties of the board.
Definitely go for the Pro if you can... if you NEVER intend to try a multi-card config, the non-pro could be viable, but it is an inferior board.
EDIT: To chip in my experience...
L040B208 batch retail (D2) i7 2600K + Asus P8P67 Pro motherboard
I find the following settings to provide the best stability at any given voltage/OC:
CPU Current Capability: 130%
Load Line Calibration: Ultra High
Phase Control: Extreme
Duty Control: Extreme
Multiplier "By all cores" (this doesn't seem to have any effect on the OC whether it's set to that or "by per core")
I then set my RAM to stock volts/settings and the vCore/multi to what I want and give it a shot...
So far I'm finding I need 1.395v (set in BIOS) with these settings to maintain full stability in games, prime, linxx, and intel burn test... it will pass 25+ runs of max IBT with lower but then crash in a game later with a bluescreen with 1.380 set. I think 4.8ghz is where I'll be nailing things down for a 24/7 OC... temps get too high for my liking if I pop up to 5ghz/1.425v (not stable yet at that point but it boots and can run a little stress testing) on my relatively puny Xigmatek S1283 HSF. I'd give it more effort with a better sink... but for now it'll do as is.




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