Well it all comes down to encryption used, if you use industry's standard AES encryption , Intel has build in hardware acceleration, nothing even comes close to speed gains, if i am not mistaken all Intel 32nm CPUs will have AES acceleration.
A 2xCore i5-650 with AES beats 12xCore opteron by ~2.48 times, and sandy bridge takes it to a new level.
You could have your OS and all partitions encrypted with AES and you would not even notice performance hit. For a regular Joe it doesn't matter but for those who want it its awesome.
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