ahh isn't that everyones question??? haha good luck because its the debate of the year i think... i guess for starters, what do you do most of the time with your computer?? if gaming, i guess 285s but if folding etc, 295s, either way, 295's are extremely impressive in their own right, but 285's for pure screaming power....

again, this is me on an "xtreme" mode...
the asus mars- dual 285's in 295 configuration = 285's in quad sli.... total beast

but theres only a limited number, around 1000??? i think.... check it out HERE