I would highly recommend the Intel Skulltrail. I have one running 24/7 on a watercooled rig at 4Ghz using 2 QX9775's. I had it at 5ghz 8 cores on vapor but have since moved it to water. It is an extremely reliable platform. I even had my E5430's running perfectely at 3.2 Ghz with minimum voltage increase. It does not like high FSB's and personally I wouldn't even try anything higher than 410 FSB.

I have since gotten this Asus board hoping to get more performance out of my E5430's. Although I can run it at 3.2 Ghz , it will not prime more than a couple of hours. I then went down to 3 Ghz and also it will not prime for more than a couple of hours. I guess I will have to go to default speed now and maybe order a new D5400xs. Not being able to use LGA 775 HSF's is a real pain in the ass and had I known that I wouldn't even have dreamed of getting this Asus. The Noctua HSF for LGA 771 would cost more than the additional cost for spending a bit more and getting a D5400XS.

The only thing I like about the Asus is that it is a small motherboard and will fit in almost any case. That is unfortunately not true with the Skulltrail ... I had to shop very hard to be able to get something that would fit that motherboard.