If you can keep the board stable and temps manageable then why not. Do you need that much for starters, I've never needed more than 1.36v Vnb on a P45 and that was with over 470fsb, q6600 and 2gb ram sticks.

Ahh that would explain it! The 38mm Delta i'm using is a ~130cfm 2800rpm unit, got a 210cfm 3700rpm 38mm as well but it sounds like an aircraft taking off its so loud, so it just sits in a box.