if it does not save the clock changes, there is the problem...have you pop the battery out with the power cord unplugged from the PSU while clearing CMOS?...don't forget to hit the power button to unload the caps from the board and PSU...leave it for 5-10 minutes.

if this does not correct the problem, disconnect all extra hardware other than the bare minimum: memory, VC and CPU...now, enter the bios and try to change the clock a small amount to see if it saves...good luck!