Well I can state that some CPU 's prefer a very low setting in FSB Term or CPU VTT and even CPU PLL... most peeps think that more voltage is required to get a CPU stable, well with 45nm it can be totally the other way around...

My E8400 was before at 1.6PLL and 1.26 VTT and needed 1.26 Vcore to be stable at 4ghz, ow I used 1.52 PLL and 1.2 CPU VTT and now it only needs 1.22Vcore to be prime stable... all these voltages seem to be connected some way or the other... I have had other wolfdales and yorks where I needed to pump way more volts to get stable...

Till now I didn't need to go over 1.35 CPU VTT to get any CPU stable at 500FSB and I only had my first Qx degrade in a few weeks due to the 780i with it's underpowered circuitry.... there's a burn in period like also found out in this thread.. but I take it slow and don't push the CPU's direct up to 4Ghz and beyond anymore... first a fw weeks at moderte clocks and then see if she can hold it...

Think about it MORE isn't ALWAYS better...