Best way to go for you is a more simple board and a good quadcore.
Skulltrail has slower memoryt then most other boards, and especially DDR3 board.

Also 3D performance is lot slower, don't know about the folding @ home performance on the new GPU client, and I don't know if you are going to use it. But buying a skulltrail and putting 2 dualcores in it, is like giving a ferrari to my bad... still slow.