Pulled my S2E out again to play around with my E8400, and have had a better time, although there are some serious FSB holes...

ASUS Striker II Extreme
CellShock DDR3-1800
nVidia 8600GT
WD RaptorX 150GB
ALL AIR COOLED
CPU - Arctic Cooling Freezer Pro 7
S2E - Stock cooling

ALL TEST: Unlinked, Memory speed locked at 1800 8-7-6-21 1.9V
ALL VOLTAGES: AUTO except CPU/RAM and stated otherwise
P1 P2: AUTO

FSB 333 - default - boot - stable
FSB 425 - no boot
FSB 450 - no boot
FSB 500 - boot - 100% stable - no corruption
FSB 525 - boot - 100% stable - no corruption
FSB 550 - boot - 100% stable - no corruption
FSB 575 - bumped VTT - Boot - not stable - no corruption

All of the above settings had crappy bandwidth, 8000 read 11500 write 74ns.

With P1P2 Enabled the board behaves very erratic.. if you manages to post, then the system seems stable, with memory performance on par with EVGA reference 790i.

Swapped out the E8400 and fitted a Q6600.

First Boot: FSB 450 x8 - boot - restarted after 20min of ORTHOS
after that all went into crap... with the same settings, it may boot, it may not. P1/P2 or not, the S2E has got an attitude problem with quads... \

HOWEVER; seems that having memory at 1800 is NOT causing corruption of the OS("is preventing OS corruption" would be too conclusive). Silver lining?