In case it might help someone - bios settings for rock stable 4GHz (8hrs Orthos Smal FFTs) on my E8500, 4x1GB Crucial Ballistix PC8000, bios 11/1, watercooled CPU/NB/SB/PWM/GPU.
Code:
CPU Feature
Thermal Management Control >>> Disabled
PPM (EIST) Mode >>> Disabled
Limit CPUID MaxVal >>> Disabled
CIE Function >>> Disabled
Execute Disable Bit >>> Enabled
Virtualization Technology >>> Enabled
Core Multi-Processing >>> Enabled
DRAM Timing
Enhance Data transmitting >>> Fast
Enhance Addressing >>> Fast
T2 Dispatch >>> Disabled
Clock Setting Fine Delay
Ch1 Clock Crossing Settting >>> More Aggresive
Ch2 Clock Crossing Settting >>> More Aggresive
Ch1Ch2 CommonClock Setting >>> More Aggresive
other subtimings >>> auto/current
CAS Latency Time (tCL) >>> 5
RAS# to CAS# Delay (tRCD) >>> 5
RAS# Precharge (tRP) >>> 4
Precharge Delay (tRAS) >>> 9
All Precharge to Act >>> 4
REF to ACT Delay (tRFC) >>> 30
Performance Level >>. Auto
Read delay phase adjust >>> auto (all)
MCH ODT Latency >>> 1
Write to PRE Delay (tWR) >>> 12
Rank Write to Read (tWTR) >>> 10
ACT to ACT Delay (tRRD) >>> 3
Read to Write Delay (tRDWR) >>> 8
Ranks Write to Write (tWRWR) Auto
Ranks Read to Read (tRDRD) Auto
Ranks Write to Read (tWRRD) Auto
Read CAS# Precharge (tRTP) >>> 3
ALL PRE to Refresh >>> 4
Voltage Settings
CPU VID Control >>> 1,35000
CPU VID Special Add >>> Auto
DRAM Voltage Control >>> 2,19
SB Core/CPU PLL Voltage >>> 1,640
NB Core Voltage >>> 1,430
CPU VTT Voltage >>> 1,160
VCore Droop Control >>> Disabled
Clockgen Voltage Control >>> 3,45
GTL+ Buffers Strength >>> Strong
Host Slew Rate >>> Weak
GTL REF Voltage Control >>> Enable
CPU GTL1/3 REF Volt >>> 62
CPU GTL 0/2 REF Volt >>> 60
North Bridge GTL REF Volt >>> 70
DRAM Timing
PCIE Slot Config 1X 1X
CPU Spread Spectrum Disabled
PCIE Spread Spectrum Disabled
SATA Spread Spectrum Disabled
Exist Setup Shutdown >>> Mode 2
Shutdown after AC loss >>> Disabled
CLOCK VC0 divider >>> Auto
CPU Clock Ratio >>> 8x
CPU N/2 Ratio >>> Disabled
Target CPU Clock >>> 4000 MHz
CPU Clock >>> 500 MHz
Boot Up Clock >>> Auto
DRAM Speed 333MHz/667
Target DRAM Speed DDR2 >>> 10001
PCIE Clock >>> 100MHz
PCIE Slot Config >>> 1x 1x
See 8hrs Orthos Small FFTs session below 

One more word about memory performance... After "transforming" Windows XP from LanParty P35 to X38 setup without reinstall, memory performance looks like this... I think that system reinstall might help (a lot)... Although I do not care for every MB/s - try to focus on Voltages optimisation

Hope it helps someone
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