I recently figured out my problem. Apparently having Speedfan in my startup list breaks Crossfire on boot. Once I removed that, let Crossfire initialize and start Speedfan manually, I was back in business. Before that the only way to play games was to have Crossfire disabled or Catalyst AI turned off - both resulted in craptastic FPS.
Haven't reinstalled 3DMark since figuring out this problem, but I'll get on that shortly.
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