Mounted my noctua nh-d14 on my Asus R3E a few days ago.
It was a tight fit, but it worked fine after removing 2 headspreaders on my Corsair memory.
I also moved one fan a littlebit higher up.

all water is now gone from my system. I've had GFX, Chipset and CPU cooling in the past 6 years, but now it's air again!