I'm keeping my 2600K at it's sweetspot. Which is 4.5 at 1.28Vcore, for 4.6 I need 1.33ish and temps go up pretty steep (all on high end watercooling).

For benching preps I use 1.5Vcore for 5.2. It's 3D stable then...

I honestly feel daily usage won't rapidly degrade the chip (except folding 24/7), but all this uber stability testing does more harm then good...