As far as I know most setups will probably have a hard time accomodating two in cross fire. Sure the Spitfire heatsink can be directed upwards but I dont think the VRM heatsink will be able to. If im true in stating that then you will very limited with PCi-e slots. Plus if the top card has the heatsink facing up it'd interfere with most heatsink towers these days. Sue you could get a low profile one but I dont think most would think it'd be a viable option.
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