After you reboot does RealTemp appear normally?

This might be caused by the ATI code I added. You can try adding this to your RealTemp.ini file next time you have a problem.

NoATIGPU=1

I plan to make the ATI code optional in the near future. It samples my 5770 with no problems but for other combinations it's hit and miss. It might work OK when not in CrossFire but might choke when you are in CrossFire. I was hoping ATI would release a driver by now that would magically fix a few things. Did you update to 10.1 recently or are you using an older driver?