Great Motherboard this - I have this board and recently upped the BIOS from 14 to the beta 18 as I am planning an upgrade or two.

Current Rough Specs are as follows

Core 2 E6300 (running at 2.9Ghz)
8Gb OCZ RAM
PC Power and Cooling 750W PSU
X1900XT (512Mb) Gfx Card
A few Tb of HDDs
20 Inch Belinea TFT

I have just order a nice 4870 1Gb Card and that will be here soon, the next major update is the main heart of the box - thinking quad QX9550 anyone been from roughly a E6300 to quad?

Any really major plus points to everyday computing/gaming or is it still video encoding/folding etc that gains the most?

I was considering the 9450 but its only 20 quid cheaper where I am. If I'm spending £200 then may as well go to the top of this motherboards line.

I'm just doing a patch-upgrade before I rebuild totally around 32nm - 2010/2011 time.