Try lowering GTLs if you run into trouble early on. The E8400 I put in there didn't like 445*9 at first, but when I set GTLs to 0,63x instead of 0,67x while leaving the VTT at 1,1V it worked like a charm. Also running 2x2GB@1066 with only 1,34V NB set in bios.
I really like the board, just 1 issue: You MUST disable EIST (speedstep) it's buggered.. if you enable it, the DFI will substantially raise the Vcore if loaded (like 1,2V bios setting, load >1,3V). Really annoying.