Best bet really seems to be cutting holes. Cutting the hole in the bottom would allow you to flip the PSU and move the cables closer to the "back" of the case. This will help with length a little, and moves the cables out of the limelight. As for the 8pin, you could always buy an extension cable to keep from having to run over the top of the video card. That's what I did with my 4pin cable.

I have a Rev 1 case without holes at all, so my only option is to cut holes. Gonna be a project that I am FINALLY starting in a couple weeks!!!