Guys I've been reading and reading and still can not make full sense of it all.
I will post below the setting I run 100% stable
Can you please analyse/criticise/recommend the settings?
Basically tell me what is wrong with them and what values they should be.
Once I get the hand of this on my mobo then I can go back and re-read this thread in regards to 0.6X multipliers, which voltage shoud by higher than vcore etc.

Rampage Extreme 501 bios
4 x 2 Diablo D9GTR based
QX9770

Extreme Tweaker Menu

CPU FSB - Manual
CPU Level Up - Auto
FSB: 430
-cpu configuration
-cpu clock skew - Auto
-nb clock skew - Auto
FSB Strap to North Bridge - 333
DRAM FREQUENCY - 1721
DRAM Command Rate - Auto
DRAM Timing Control - Manual
*1st information : 8-7-6-15-Auto-Auto-Auto-Auto
*2nd informaion : all AUTO
*3rd information : all AUTO
DRAM Static Read Control - Auto
DRAM Dynamic Write Control - Auto
-DRAM Skew Control
Ai Clock Twister - Auto
Ai Transaction Booster - Auto
*C/P : A1 A2
*LVL : 07 07

EPU II Phase Control - Auto
-----------------------------------------------------------------
*** Please Key in Numbers or select voltage!***
CPU Voltage - 1.462
Load-Line Calibration - Enabled
CPU PLL Voltage - 1.709
FSB Termination Voltage - 1.45
CPU GTLVref (o) - +40
CPU GTLVref (1) - +50
CPU GTLVref (2) - +50
CPU GTLVref (3) - +40
NB GTLVref - +30
North Bridge Voltage - 1.66997 (needs to be this high due to 8GB DDR3)
DRAM Voltage -1.96156
NB DDRVref - Auto
DDR3 ChannelA Vref - Auto
DDR3 ChannelB Vref - Auto
South Bridge 1.5 Voltage - 1.6
South Bridge 1.05 Voltage - 1.08
**********************************************
CPU Spread Spectrum - Disabled
PCIE Spread Spectrum - Disabled

Thanks.