I can't help you as far as limitations for the upgrade, but i personally just recently bought the OEM Vista 64 bit from newegg.
I would think you can install it on multiple systems.
The DVD can't tell if its being installed on another system. But you are only allowed ONE activation. meaning if today, you decided to install vista64 on Computer1, but then later you want to trash Computer1 and install vista64 on Computer2, then you will need to actually call microsoft, and tell them you are installing on a new compy and revalidate ur activation. Then install on Computer2.





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