really depends on the mounting holes, if they line up with anything from the past (like how the 8800gt lined up fairly well with the 7900gt but not 8800gtx), then perhaps you can get it to work, but it should have a pretty good stock cooler because of the large die size, I doubt you'll find better short of paying ~$50 for something like an hr 03 uber extreme gtx 280 edition or whatever thermalright plans to make