My current S2E works without touching vtt ot gtl. I'm running e8400 @ 4.1 (1840 1.328v) Prime and OCCT stable and the only thing I've changed are cpu/ram voltage and manually set the timings. My 3rd mobo crashed in seconds no matter what vtt/gtl combination but it never corrupted anything. And I've tried them all for 2 days. And the first two corrupted Windows like now tomorrow, change anything in bios and Windows will go away. I decided to sell it while it's working and "docile". Trust me, this mobo is a weird animal.LOL!!