rare to burn a quad up, it happens though. Usually only on sucide runs for extended time, or with people into LN2 stuff really pushing chips, even then you dont see or hear much about them going south, the cpu is probably the most reliable piece in a build, you would be surprised how much abuse they can take nowdays.

ram on the other hand isnt so tuff, or most boards for that matter

71c is the max recommended by intel for 24/7 use at 1.35v