You can, but it is not recommended. If they are totally different IC's then you may get tons of errors. If they are the same brand and same IC's then you have a good chance, but it would not be good to overclock in four dimms for many sticks. For example, I have Corsair pc8500C5's and Dominator pc8500C5D's. In 4 dimms, it runs stable at ddr800 although it can go up to 1066, but overclocking is not becoming of this setup.




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