This is XS Micutzu. But your point is well noted. FYI, my sticks have done 2.4v 24/7 for a good 7 months or so and are no worse for the wear. When benching I give them 2.8V regularly, and 2.9 when I wanted 500MHz CAS 3. That was a very short period of time.

One thing you can notice about Black's equation is that its inverse exponential with respect to absolute temperature. Keep your semiconductor device cool, and its lifetime dramatically increases. 24/7 I've got a 90mm on my sticks, and when benching usually something pushing at least 110CFM if not close to 200.

Something else that I think is of concern is voltage regulation. Lots of boards these days IMHO regulate vdimm pretty crappily, and this is probably the cause of death at even lower vdimms. The Bad Axe 1 is the most notorious example of this, murdering ram past 2.2v set as it would periodically spike past 3V due to the low current mosfets used.