Decade of Discovery: A new drug lead to combat dengue fever

By: Dr. Stan Watowich, PhD
University of Texas Medical Branch (UTMB) in Galveston, Texas
10 Nov 2014

Summary
For week five of our decade of discovery celebrations we?re looking back at the Discovering Dengue Drugs - Together project, which helped researchers at the University of Texas Medical Branch at Galveston search for drugs to help combat dengue - a debilitating tropical disease that threatens 40% of the world?s population. Thanks to World Community Grid volunteers, researchers have identified a drug lead that has the potential to stop the virus in its tracks.
We have recently made an exciting discovery using insights from Discovering Dengue Drugs - Together to guide additional calculations on our web portal for advanced computer-based drug discovery, DrugDiscovery@TACC. A molecule has demonstrated success in binding to and disabling a key dengue enzyme that is necessary for the virus to replicate.
Full article at link.