I wouldn't recommend it. You might find some obscure model out there that will boot up "off the shelf," but the community mainly supports Gigabyte motherboards, and those are the boards you'll be able to use custom DSDTs with from the online database, which really simplifies the whole process. Furthermore, OS X only has support for a very limited number of graphics cards, pci cards, etc, so anything "off the shelf" is likely to need some modification to achieve full functionality. You're better off hand-picking each piece of hardware if you want to assure compatibility. Keep in mind that this process isn't supposed to be easy - Apple really doesn't want you to build your own mac and will do everything possible to prevent it.
I recommend checking out http://tonymacx86.blogspot.com/
As far as bios settings go, I'm using a Sandy Bridge hackintosh, and I had to make sure AHCI was enabled as well as turn on 64 bit HPET.



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