The difference between the two in most titles is between 2 and 5 fps at GTX 460 stock speeds in sli. On a faster card the difference should become a bit more pronounced, but as you pointed out earlier the GTX 460 already scales amazingly well in the first place.2gb just keeps that scaling percentage at ultra high resolutions.
Also, running dual cards is more likely to hit the ceiling where 2gb comes in handy because it has the horse power to hit those ceilings vs 1 card that may not be fast enough to reach that point.
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