bobly, im having similar difficulties with my S2E. We have the same ram, but i ahve a E8600, which i cant get above 4ghz. Ive tried pushing the Vcore up to 1.45, even 1.5 at some points and it still wasnt stable... tried increasing both NB and SB voltages, still unstable... im kinda stuck in a predicament, trying to figure out what has gotten me stuck, but i just cant figure it out. Im thinking it might be my ram... on stock cpu settings when i input the timings manually it runs, but if i raise the cpu settings even by 1fsb (from 333 to 334) it becomes unstable... Should i try loosening the ram timings?