Start from beginning and keep it simple, cool the CPU first and only and by the time you get used to it you hole mobo will be taken.
No need to worry today's blocks are very secure especially if you go for the top quality ones and even when you have a leak the mobo will shut down because of the high temps and the fluid won't harm any of your circuits because it's non-conductive.
I've read about cases here in XS Forum that ppl running WATER got a leak from a crappy block and it really shorted the board, the guy just unplugged everything and let it dry in the sun and everything worked like wonders again.
Just avoid cheap stuff below look for brands like Dtek, Swiftech, EK, Hardware Labs black Ice etc you'll be fine.







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