On new mainboards Q9300 overclocks only to 3.3-3.5GHz, E8400 can reach 4.2-4.4GHz. Take a mind that P5W can't work on very high FSB, so it's always nicer to get a CPU with higher multiplier, but also P5W very often overclocks even lower with Quads than with Duos.
I have to choose between Q9450/Q9550 and E8500, at last I choose cheeper E8500 and now wait for it
So first of all see that tacks you have, if they are not designed for 3-4 cores, then get Duo, it will be always faster, if your tacks have a little optimization for 3-4 cores, then extra MHz from Duo will help you not to work slower than Quad or even a bit faster.
Also Q9300 have only 3MB of L2 cache per crystal, all other E8XXX and Q9XXX have full 6MB L2 cache, which add a little more performance if your tack works only with 1 or 2 threads than compare between E8XXX and Q9300 at the same clock.





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