Nope, the PA160 won't cool a quadcore by itself. However, if you add a fan to it it might... and it's the fan that determines whether it will cool it and how much it will cool it.

The hint there being, state the fan you intend to use.



Pf H = Panaflo FBA12G12-H1A - 105cfm, 6.8mmH2O, 41.5dBA
1212M = Delta WFB1212M - 72.4cfm, 3.4mmH2O, 34dBA
Nexus = Nexus D12SL-12 - 36.8cfm, 22.8dBA

Quadcore = 130w @ stock = 253w @ 3.6Ghz with 1.5v