Well I decided to put the card in my Badaxe which is now in my media server and it didn't make the strange noise I have been hearing. Anyway to cut a long story short its coming from my Seasonic 600W. Funny thing is the PSU was the first thing I thought I had checked. The 600W Seasonic in my MCE doesn't make the same noise. PSU's I can sort we have loads at work so no hassle in the end. Now I can enjoy the card.

Thanks for the help peeps. Its much appreciated