Boinc 7.4.26 has ASIC support.

[PoppaGeek]

ASIC support added to Boinc

Changes in 7.4.26/7.4.27

Add support for notices that contain images and videos.
Add support for generic OpenCL devices. (Parallella, etc.)
Add support for ASIC Miners.
Add new AMD GPU descriptions.
Add new Windows version descriptions.
Add support for Mac OS X 10.10 (Yosemite)
Add support for Windows 10

ASIC Miners

BOINC now has support for ASIC Miners. An ASIC (application-specific integrated circuit) is a device that is specialized to perform a single task very quickly, and a miner is a device that mines cryptocurrencies like Bitcoin in order to generate value.
To configure an ASIC Miner coprocessor type in BOINC, you will need to add a "coproc" XML element to your cc_config.xml configuration file, including child elements for type and count. Type should be miner_asic, and count should be the number of such devices that you plan on using in BOINC. Additionally, depending on the project and the application, you may need to specify certain application command line parameters in an app_config.xml file, in order to properly run multiple ASIC Miners or to overclock them. See BOINC Configuration for general information on configuring those files.
Bitcoin Utopia is a BOINC project that has developed applications designed to utilize this new resource type. Please see their website and forums, for details and support.

The project also has to support ASIC.

ASIC run very fast doing one thing thing only. For the work they do they can be as cheap as $15 and use extremely little electricity. They can also cost thousands and heat an auditorium.

They also require a controling PC. Raspberry Pies are popular as controllers.