Imho simplest is to copy-cat some of leading blocks, eg.
EK Supreme HF. 1.9-2mm deep 49 thin channels (but probably the thinner/more channels you can cut, the better). IIRC Old supreme block and HK 3.0 had shallower, about 1.5mm, which resulted in more flow restriction. No sense in making channels much deeper too, as further from base of block/from cooled CPU, less heat is conducted from it to top ends of fins. Couldn't find though how wide those channels & fins are and how thick is base of HF. Base of waterblock should be thin as possible for better heat conductivity (and lacking resulting rigidity should be compensated by top pushing through O-ring on waterblock's base with channels.
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