Guys, I would not use either the 7.21 or 7.22. Seems MSI is trying to pull a quick one on us by relaxing the memory timings. I've tested the 7.21 bios set at 4-4-3-8 and memset and cpu-z reads 4-5-6-8 and indeed thats what my board is running. Ran 3dmark at those settings then used memset to 4-4-3-8 and ran a much much faster.
Bottom line this board is only worth getting if you have a e6600 or higher. Dam a e6700 at 400x10 seems very tempting.