To start with perhaps but as heterogeneous multicore becomes the dominant architecture, it (Fusion, Cell & Nehalem) will become a threat to the discrete market and possibly the desktop market, consider that laptops now represent
53% of the PC market and that the same was said about more simplistic floating point co-processors, memory controllers and even multicore processors.
To say that CUDA has nothing to do with this is naive, nVidias progress with CUDA is all about increasing the dependence of the PC user on discrete graphics solutions in order to slow the adoption of Intel's new non-SLi compatible processor and maintain their relevance through the third round of the core wars.