Originally Posted by
churchy
I'd go for #1, as shortest/simpliest tubing routing. I don't get much why you like 4th, with going extra up-and-down without much extra need for that.
And hmm, shouldn't rad in lower compartment be turned with inlets in middle of case, so that tubing can be passed through holes for wire managment?
Also be careful with selecting tubing width. Check if selected tubing size OD (and it's fittings, if some of them will be placed there too) fits well behind motherboard tray and other areas, where you plan to route tubing.