I'll give it a shot again, but I think this can work out quite well.
- Rotate the res about 10~15 degrees towards the motherboard, put a 90-deg rotary fitting on the top side of the GPU block, put tubing directly between the res and the GPU - a straight shot.
- Keep the GPU -> CPU routing
- Keep the CPU -> Rad routing
- Put a 45-deg rotary fitting on the rad farthest from the motherboard, connect to the pump - a straight shot.
http://img268.imageshack.us/img268/2836/87798160.jpg
I think this would look much cleaner and spacious.