FSB is the botlleneck of the quads, higher FSB at same speed will give you higher performance. All can be done in the limits off the quad and mobo. With proper settings, it is usually the cpu that hits a wall. Some worse cases cant go higher than 420, very good quads can go 480+
Try some testing yourself: set a low multi, relax memory timings, etc. - make sure, that nothing else will be an obstacle for high fsb freqs. Now start at 450 and go up p up .... adjust voltages, check temps .... you get the point. Mostly, for 450 and up, you may require high voltages for fsb, mch or vtt, pll, find your comfort zone for the particular cpu for 24/7