All my loops generally go Res>Pump>Rad>Block and this is no exception.
The GPU loop is off the bottom mounted MCR320. I am assuming that the large surface area will make up for the fact there are only really two fans on it (the PSU also...but it's hardly drawing that much air).
The chipset coolers are running off the PA1650. Now since I can cool and OCed quad off a single PA160 I feel that even though this rad is picking up the warmed air from the MCR320 below it will still perform adequately. The blocks are in series and to keep the tubes as short as possible go from Rad to SB to NB back the res.
The CPU is handled by the top mounted MCR220...this rad gets the benefit of thermal convection plus a pair of 140mm fans. Despite having a pre-warmed airstream I hope that it will be enough. It would have been a lot more work to mount a 320 up top..taking up a great deal of internal space, losing the top two optical bays and so forth...so I had to compromise here.
The airflow is all bottom to top. The case floor does allow for some fresh (non rad-pass air) through a grill in the very front. So I added a powerful fan above the HDD/Pump compartment to do several things: get some fresh air, help draw air through the PA160, cool the Raptor X drives and Cool the larger storage drive, and (I hope) provide a slight temp drop in the internal case air.
Right now my main concern is the lack of side panel fans: although this does make the case quieter it will likely make any non-LC components a lot warmer. But my hope is the airflow will be adequate withou any more fans...