Grafting name brand/proprietary motherboards into generic cases?

Hey all,
I am looking at some really good priced multisocket server motherboards from Dell and HP. Has anyone ever tried using a proprietary/name brand mobo in a generic server case? (In this case, a 4U server case). Was it easy, were there any problems with things like on/off and reset buttons, etc?

late response, probably not easy
my guess without specifics is that you'll need to drill and tap holes into the mobo tray at a minimum and install standoffs, fabricate io shield, possibly fabricate pci / pcie expansion brackets.